[5]吴正治,等. 南非专利:A PRECISE MEDICATED DIET PRODUCT FOR RHEUMATOID ARTHRITIS AND A PREPARATION METHOD THEREOF(新冠病毒(2019-nCoV)早期快速诊断分子机器人构建方法),国际专利号:2022/02394,授权时间:2022年5月25日
[6]吴正治,等. 南非专利:NOVEL CORONAVIRUS (ORF1AB GENE) DETECTION PRIMER PAIR AND APPLICATION THEREOF((ORF1ab)检测新型冠状病毒的引物对及其应用),国际专利号:2022/08145,授权时间:2022年11月30日
[7]吴正治,等. 南非专利:REFERENCE GENE RP DETECTION PRIMER PAIR AND APPLICATION THEREOF(RP内标基因检测引物对及其应用),国际专利号:2022/08149,授权时间:2022年11月30日
[8]吴正治,等. 南非专利:NOVEL CORONAVIRUS (N GENE) DETECTION PRIMER PAIR AND APPLICATION THEREOF((N基因)检测新型冠状病毒的引物对及其应用),国际专利号:2022/08147,授权时间:2022年11月30日
[9]吴正治,龙伯华,李利民,李芷悦,刘展艳.国际发明专利(美国):Total synthesis of a Natural Active Peptide Tubulysin U.一种天然活性多肽Tubulysin U的全合成制备方法,美国专利号:17984642,授权时间:2023年
[33]吴正治,等. 澳大利亚革新专利:A Traditional Chinese Medicine Composition With Preparation Method And Application Thereof(一种中药组合物、制备方法和应用),国际专利号 :2021106260,授权时间:2021年10月20日
[34]吴正治,等. 澳大利亚革新专利:a medicinal diet composition for hypertension and preparation method thereof (一种用于高血压病的药膳食疗组合物及其制备方法),国际专利号 :2021106255,授权时间:2021年10月20日
[35]吴正治,等. 澳大利亚革新专利:a medicinal diet composition for preventing and treating hyperuricemia and gout (防治高尿酸血症和痛风的药膳食疗组合物及其制备方法),国际专利号 :2021106230,授权时间:2021年10月20日
[36]吴正治,等. 澳大利亚革新专利:a medicinal diet composition for type 2 diabetes and preparation method thereof(一种用于2型糖尿病的药膳食疗组合物及其制备方法),国际专利号 :2021106244,授权时间:2021年10月20日
[37]吴正治,等. 澳大利亚革新专利:medicinal diet product composition for hyperlipemia and fatty liver and preparation method thereof (用于高脂血和脂肪肝的药膳食疗产品组合物及其制备方法),国际专利号 :2021106305,授权时间:2021年10月20日
[38]吴正治,等.南非专利:A CHINESE MEDICINAL COMPOSITION FOR STRENGTHENING BODY RESISTANCE, ANTIVIRAL AND EPIDEMIC PREVENTION, AND ITSPREPARATION METHOD(一种扶正抗毒防疫药食同源中药组合物及其制备方法),国际专利号 :2021/06786,授权时间:2021年10月27日
[39]吴正治,等. 南非专利:METHOD FOR PREPARING POLYPEPTIDE TUBULYSIN M WITH HIGH ANTI-TUMOR ACTIVITY(一种高效抗肿瘤活性多肽Tubulysin M的制备方法),国际专利号 :2021/07061,授权时间:2021年11月24日
[40]吴正治,等. 南非专利:A PRODUCT COMPOSITION OF PRECISION MEDICATIVE DIET FOR PREVENTING AND TREATING PREMATURE OVARIAN FAILURE AND PREPARATION METHOD THEREOF(一种防治卵巢早衰的精准药膳食疗产品组合物及其制备方法),国际专利号:2022/02639,授权时间:2022年5月25日
[41]吴正治,等. 南非专利:A KIND OF PRECISION PRODUCT COMPOSITION OF MEDICINAL DIET DIETOTHERAPY FOR SLEEP DISORDER AND PREPARATION METHOD THEREOF(一种用于睡眠障碍的精准药膳食疗产品组合物及其制备方法),国际专利号:2022/02707,授权时间:2022年5月25日
[42]吴正治,等. 南非专利:A PRODUCT COMPOSITION OF MEDICINAL DIET DIETOTHERAPY FOR PREVENTING AND TREATING DEPRESSION AND PREPARATION METHOD THEREOF(一种防治抑郁症的药膳食疗产品组合物及其制备方法),国际专利号:2022/02709,授权时间:2022年5月25日
[43]吴正治,等. 南非专利:A CHINESE MEDICINAL COMPOSITION FOR PREVENTING AND TREATING MALIGNANT TUMOR, AND ITS PREPARATION METHOD AND PREPARATIONS(一种用于防治恶性肿瘤的中药组合物、制备方法及其制剂),国际专利号:2022/02708,授权时间:2022年5月25日
[44]吴正治,等. 南非专利:METHOD FOR PREPARING POLYPEPTIDE TUBULYSIN M WITH HIGH ANTI-TUMOR ACTIVITY(用于类风湿性关节炎的精准药膳食疗产品及其制备方法),国际专利号:2022/06459,授权时间:2022年8月31日
[45]吴正治,等. 南非专利:A PRECISE MEDICATIVE DIET FOR FOOD THERAPY FOR PREVENTING AND TREATING FUNCTIONAL DYSPEPSIA AND ITS PREPARATION METHOD(防治功能性消化不良的精准药膳食疗产品及其制备方法),国际专利号:2022/06460,授权时间:2022年8月31日
[46]吴正治,等. 南非专利:A PRECISE MEDICATED DIET AND FOOD THERAPY PRODUCT FOR CHRONIC HEPATITIS AND A PREPARATION METHOD THEREOF(用于慢性肝炎的精准药膳食疗产品及其制备方法),国际专利号 :2022/06503,授权时间:2022年8月31日
[47]吴正治,等. 南非专利:PREPARATION METHOD OF DOCETAXEL CHIRAL SIDE CHAIN INTERMEDIATE(一种多西紫杉醇手性侧链中间体的制备方法),国际专利号 :2022/06555,授权时间:2022年9月28日
[48]吴正治,等. 南非专利:ACCURATE MEDICATED DIET PRODUCT FOR PREVENTING AND TREATING SENILE FUNCTIONAL CONSTIPATION AND PREPARATION METHOD THEREOF(防治老年功能性便秘的精准药膳食疗产品及其制备方法),国际专利号 :2022/06556,授权时间:2022年9月28日
[49]吴正治,等. 南非专利:EFFICIENT PREPARATION METHOD OF CYCLOTHEONELLAZOLE A CORE SKELETON AND ITS DERIVATIVES(Cyclotheonellazole A核心骨架及其衍生物的高效制备方法),国际专利号 :2022/06557,授权时间:2022年9月28日
[50]吴正治,等. 南非专利:ACCURATE MEDICATED DIET FORMULA FOR HARMONIZING PHYSIQUE AND PREPARATION METHOD THEREOF(一种用于平和体质人群的精准药膳食疗配方及其制备方法),国际专利号:202300087,授权时间:2023年3月29日
[51]吴正治,等. 南非专利:ACCURATE MEDICATED DIET FORMULA FOR QI DEFICIENCY PHYSIQUE AND PREPARATION METHOD THEREOF(一种用于气虚体质调理的精准药膳食疗配方及其制备方法),国际专利号:202300088,授权时间:2023年3月29日
[52]吴正治,等. 南非专利:ACCURATE MEDICATED DIET FORMULA FOR YANG DEFICIENCY PHYSIQUE AND PREPARATION METHOD THEREOF(一种用于阳虚体质调理的精准药膳食疗配方及其制备方法),国际专利号:202300089,授权时间:2023年3月29日
[53]吴正治,等. 南非专利:ACCURATE MEDICATED DIET FORMULA FOR PHLEGM-DAMPNESS PHYSIQUE AND PREPARATION METHOD THEREOF(一种用于痰湿体质人群的精准药膳食疗产品配方及其制备方法),国际专利号:20230009,授权时间:2023年3月29日
[54]吴正治,等. 南非专利:ACCURATE MEDICATED DIET FORMULA FOR DAMP HEAT PHYSIQUE AND PREPARATION METHOD THEREOF(一种用于湿热体质人群的精准药膳食疗产品配方及其制备方法),国际专利号:202300091,授权时间:2023年3月29日
[55]吴正治,等. 南非专利:ACCURATE MEDICATED DIET FORMULA FOR YIN DEFICIENCY PHYSIQUE AND PREPARATION METHOD THEREOF(一种用于阴虚体质人群的精准药膳食疗产品配方及其制备方法),国际专利号:202300196,授权时间:2023年3月29日
[56]吴正治,等.尼日利亚专利:Formula of Accurate Medicated Diet Therapeutic Product for the Constitution with Qi-blood Deficiency andIts preparation Method(一种气血两虚体质精准药膳食疗产品配方及其制备方法),国际专利优先号:110852484138,授权时间:2023年
[57]吴正治,等.尼日利亚专利:Formula of Accurate Medicated Diet Therapeutic Product for the Constitution with Qi-yin Deficiency and Itspreparation Method(一种气阴两虚体质精准药膳食疗产品配方及其制备方法),国际专利号:280852260563,授权时间:2023年
[58]吴正治,等.尼日利亚专利:Formula of Accurate Medicated Diet Therapeutic Product for the Constitution with Blood Deficiency andIts preparation Method(一种血虚体质精准药膳食疗产品配方及其制备方法),国际专利号:130852337049,授权时间:2023年
[59]吴正治,等.尼日利亚专利:Formula of Accurate Medicated Diet Therapeutic Product for the Constitution with Qi Stagnation and Itspreparation Method(一种气郁体质精准药膳食疗产品配方及其制备方法),国际专利号:240865371206,授权时间:2023年
[60]吴正治,等.尼日利亚专利:A personalized medicinal food therapy composition for special constitutions and its preparation method(一种特禀体质精准药膳食疗组合物及其制备方法),国际专利号:110867091719,授权时间:2023年
[61]吴正治,等.尼日利亚专利:Formula of Accurate Medicated Diet Therapeutic Product for the Constitution with Blood Stasis and Itspreparation Method(一种血瘀体质精准药膳食疗产品配方及其制备方法),国际专利号:340865359841,授权时间:2023年
[62]吴正治,等.尼日利亚专利:Preparation and application of an antiviral solid perfume extracted from traditional Chinese medicines(一种中药防疫固体香的制备与应用),国际专利号:230865360071,授权时间:2023年
[63]吴正治,等.尼日利亚专利:A non-rinse hand sanitizer with antibacterial and moisturizing functions, as well as its preparation method(一种中药抗病毒免洗洗手液的制备与应用),国际专利号:310872171713,授权时间:2023年
[64]吴正治,等.南非专利:MINIMALLY INVASIVE SURGERY ROBOT WITH DOUBLE ENDOSCOPES AND OPERATION METHOD THEREOF(一种具有双内视镜的微创手术机器人及操作方法),国际专利号:2021/06846,授权时间:2021年11月24日
在国内外核心期刊发表专业学术论文342篇,影响因子736.394分,被引用3000余次,其中SCI TOP Q1顶级期刊论文38篇,IF最高21.566分。
[1]Changqun Liu, Yuening Cao, Yi Zuo, Chaozheng Zhang, Senmiao Ren, Xin Zhang, Chuanqi Wang, Yingjie Zeng, Jie Ling, Yilan Liu, Zixian Chen, Xiujun Cao, Zhengzhi Wu*, Chuantao Zhang*, Jun Lu* J.Hybridization-based discovery of novel quinazoline-2-indolinone derivatives as potent and selective PI3Kα inhibitors Adv. Res., 2024, DOI: 10.1016/j.jare.2024.03.002 (IF: 13.822/Q1)
[2]Wang, Lin; Zhou, Bi-Qiang; Li, Ying-Hong; Jiang, Qian-Qian; Cong, Wei-Hong; Chen, Ke-Ji*; Wen, Xiao-Min*; Wu, Zheng-Zhi*. Lactoferrin modification of berberine nanoliposomes enhances the neuroprotective effects in a mouse model of Alzheimer's disease. Neural Regeneration Research, 2023, 18(1): 226-232.(IF 6.058/Q1)
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[7]Jiangchun Wei, Zhiyue Li, Min Shan, Fengzhi Wu, Limin Li, Yucui Ma, Junhong Wu, Xinping Li, Yaqian Liu, Zhengxi Hu, Yonghui Zhang , Zhengzhi Wu*. Discovery of two ent-atisane diterpenoid lactones with AChE inhibitory activity from the roots of Euphorbia fischeriana, Organic &Biomolecular Chemistry, 2023, 21: 6949-6955. (IF: 3.2/Q1)
[8]Qi Liu, Yan Li, Peng Yang, Quanquan Liu, Chunbao Wang, Keji Chen , Zhengzhi Wu. A survey of artificial intelligence in tongueimage for disease diagnosis andsyndrome differentiation. DIGITAL HEALTH, 2023, 9: 1-25. (IF: 3.9/Q1)
[9]Bohua Long, Liuyang Pu, Zhanyan Liu, Xiaobin Zeng and Zhengzhi Wu*. Formal synthesis of Cyclotheonellazole A. Org. Biomol. Chem., 2023, 21, 3531-3536. (IF 3.890/Q1)
[10]Xin Li, Jian Chen, Kaixuan Luo, Yishan Guo, Yongxing Deng, Xianli Li, Wenjing Chen, Zunnan Huang, Jianqiang Liu, Zhengzhi Wu, Cheng Tao.Asymmetric total synthesis and anti-hepatocellular carcinoma profile of enantiopure euphopilolide and jolkinolide E. Bioorganic Chemistry.Available online 22 June 2023, 106688(IF 5.1/Q1)
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[14]Li, Weifeng; Lin, Lin; Yan, Dewen; Jin, Yu; Xu, Yun; Li, Yinghong; Ma, Min*; Wu, Zhengzhi*. Application of a Pseudotargeted MS Method for the Quantification of Glycated Hemoglobin for the Improved Diagnosis of Diabetes Mellitus. Analytical Chemistry, 2020, 92(4): 3237-3245. (IF: 8.008/Q1)
[15]Li, Yan; Wang, Chunyi; Jin, Yu; Chen, Haibo; Cao, Meiqun; Li, Weimin*; Luo, Huanmin*; Wu, Zhengzhi*.Huang-Qi San improves glucose and lipid metabolism and exerts protective effects against hepatic steatosis in high fat diet-fed rats. Biomedicine & Pharmacotherapy,2020, 126(3): 109734. (IF: 7.419/Q1)
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[31]Wang, Chunbao; Sun, Zhengdi; Long, Jianjun; Wei, Jianjun*; Chen, Xiaojiao; Liu, Quanquan*; Shen, Yajin; Shang, Wanfeng; Wang, Yulong; Duan, Lihong; Wu, Zhengzhi*.Development of a novel massage platform for medical training.Technology and Health Care, 2020, 28(S1): S89-S101.
[32]Jiang, Qianqian; Liang, Shaoyu; Zeng, Yongchang; Lin, Wang; Ding, Feng; Li, Zhongqiu; Cao, Meiqun; Li, Yinghong*; Ma, Min*; Wu, Zhengzhi*.Morphology, structure and in vitro digestibility of starches isolated from Ipomoea batatas (L.) Lam. by alkali and ethanol methods.International Journal of Biological Macromolecules, 2019, 125: 1147-1155. (IF 8.025/Q1)
[33]Fan, Dahua; Liu, Liping; Wu, Zhengzhi*; Cao, Meiqun*.Combating Neurodegenerative Diseases with the Plant Alkaloid Berberine: Molecular Mechanisms and Therapeutic Potential.Current Neuropharmacology, 2019, 17(6): 563-579. (IF: 7.708/Q1)
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[35]Zeng, Qiang; Li, Longfei; Jin, Yu; Chen, Zongzheng; Duan, Lihong; Cao, Meiqun; Ma, Min*; Wu, Zhengzhi*.A Network Pharmacology Approach to Reveal the Underlying Mechanisms of Paeonia lactiflora Pall. On the Treatment of Alzheimer's Disease.Evidence-Based Complementary and Alternative Medicine, 2019, 2019: 8706589.
[36]Li Wei-Feng; Yan De-Wen; Jin Yu; Li Hai-Yan; Ma Min*; Wu Zheng-Zhi*.Application of Mass Spectrometry in Analysis of Non-Enzymatic Glycation Proteins in Diabetic Blood.Chinese Journal of Analytical Chemistry, 2019, 47(11): 1732-1741.
[37]Sun, Kehuan; Tao, Cheng; Long, Bohua*; Zeng, Xiaobin*; Wu, Zhengzhi*; Zhang, Ronghua*.Highly stereoselective gram scale synthesis of all the four diastereoisomers of Boc-protected 4-methylproline carboxylates.RSC Advances, 2019, 9(55): 32017-32020.
[41]Chen, Piaopiao; Sawyer, Erica; Sun, Ke; Zhang, Xialin; Chen, Chuan; Ying, Binwu; Wei, Xiawei; Wu, Zhengzhi*; Geng, Jia*.A general strategy for label-free homogeneous bioassays based on selective recognition and silver ion-mediated conformational switch.Talanta, 2019, 201: 9-15. (IF: 6.556 /Q1)
[42]Jia, Dan; Li, Zi Wen; Zhou, Xinxin; Gao, Ying; Feng, Yifan; Ma, Min; Wu, Zhengzhi*; Li, Weimin*.A novel berberine-metformin hybrid compound exerts therapeutic effects on obese type 2 diabetic rats.CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, 2019, 46(6): 533-544.
[43]Zeng, Qiang; Siu, Wingsum; Li, Limin; Jin, Yu; Liang, Shaoyu; Cao, Meiqun; Ma, Min*; Wu, Zhengzhi*.Autophagy in Alzheimer's disease and promising modulatory effects of herbal medicine.Experimental Gerontology, 2019, 119: 100-110.
[44]Deng, Jiu; Zhang, Xiuli*; Chen, Zongzheng; Luo, Yong*; Lu, Yao; Liu, Tingjiao; Wu, Zhengzhi; Jin, Yu; Zhao, Weijie; Lin, Bingcheng*.A cell lines derived microfluidic liver model for investigation of hepatotoxicity induced by drug-drug interaction.Biomicrofluidics, 2019, 13(2): 024101.
[45]Chen, Piaopiao; Yan, Shixin; Sawyer, Erica; Ying, Binwu; Wei, Xiawei; Wu, Zhengzhi*; Geng, Jia*.Rapid and simple detection of ascorbic acid and alkaline phosphatase via controlled generation of silver nanoparticles and selective recognition.Analyst, 2019, 144(4): 1147-1152. (IF: 5.227 /Q1)
[46]Fan, Xiaotong; Tian, Ruizhen; Wang, Tingting; Liu, Shengda; Wang, Liang; Xu, Jiayun; Liu, Junqiu*; Ma, Min; Wu, Zhengzhi*.An ultrathin iron-porphyrin based nanocapsule with high peroxidase-like activity for highly sensitive glucose detection.Nanoscale, 2018, 10(47): 22155-22160. (IF: 8.307/Q1)
[47]Cao, Yongkai; Sun, Ningning; Zhang, Jiumei; Liu, Zhiguo; Tang, Yi-zhe; Wu, Zhengzhi*; Kim, Kyeong-Man*; Cheon, Seung Hoon*.Design, synthesis, and evaluation of bitopic arylpiperazine-phthalimides as selective dopamine D-3 receptor agonists (vol 6, pg 1457, 2018).Medchemcomm, 2018, 9(9): 1565-1565.
[48]Cao, Yongkai; Sun, Ningning; Zhang, Jiumei; Liu, Zhiguo; Tang, Yi zhe; Wu, Zhengzhi*; Kim, Kyeong Man*; Cheon, Seung Hoon*.Design, synthesis, and evaluation of bitopic arylpiperazine-phthalimides as selective dopamine D-3 receptor agonists.Medchemcomm, 2018, 9(9): 1457-1465.
[49]Liu, Qiong; Sun, Ning-Ning; Wu, Zheng-Zhi; Fan, Da-Hua*; Cao, Mei-Qun*.Chaihu-Shugan-San exerts an antidepressive effect by downregulating miR-124 and releasing inhibition of the MAPK14 and Gria3 signaling pathways.Neural Regeneration Research, 2018, 13(5): 837-845.
[50]Li, Ying-hong*; Wang, Xu-sheng; Chen, Xiao-lin; Jin, Yu; Chen, Hong-bo; Jia, Xiu-qin; Zhang, Yong-feng; Wu, Zheng-zhi.Neuroprotective effect of the Chinese medicine Tiantai No. 1 and its molecular mechanism in the senescence-accelerated mouse prone 8.Neural Regeneration Research, 2017, 12(2): 301-306.
[51]Duan, Lihong; Li, Meng; Wang, Chunbao*; Wang, Qingmei; Liu, Quanquan; Shang, Wanfeng; Shen, Yajin; Lin, Zhuohua; Sun, Tongyang; Quan, Daping; Wu, Zhengzhi*.Study on synthesis and properties of nanoparticles loaded with amaryllidaceous alkaloids.Open Life Sciences, 2017, 12(1): 356-364.
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[53]Bohua Long, Jingzhao Zhang, Xudong Tang and Zhengzhi Wu*, Total synthesis of wewakazole B. Organic & Biomolecular Chemistry, 2016, 14: 9712-9715. (IF: 3.890/Q1)
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